Leaders in the Discovery of Bioactive Dipeptides “PO” and “OG”
Over a decade ago, Wellnex was the first collagen peptide supplier to successfully identify the bioactive dipeptides proline-hydroxyproline “PO,” and hydroxyproline-glycine “OG,” from within the collagen peptide molecule.
Bioavailability trials revealed PO and OG in high concentrations within the human bloodstream following oral consumption of Wellnex collagen peptides. Additional studies confirmed accumulation of these bioactive compounds in specific tissues, including the skin and cartilage, via radio labeling. Detection of PO in human urine following consumption also indicate that these dipeptides are uniquely resistant to peptidases (enzymes that break down peptides into single amino acids) within the human body.
Building on this body of scientific knowledge, multiple human clinical trials have confirmed that collagen peptides with higher levels of PO-OG illicit greater physiological benefits, when compared to standard collagen peptide ingredients, over the same dosage and duration.
Only Wellnex Replenwell™ offers unique collagen products with up to 30 times the PO-OG content of standard collagen peptides. Ultra high levels of bioactive dipeptides lead to smaller effective serving sizes, better cost-in-use, and greater versatility in product applications.