The term “joint support” takes on various meanings depending on the genetic makeup, age, activity level, and diet of the individual in question. Just as collagen ingredients are not “one sized fits all,” neither are recommended dosages or ingestion durations for collagen-containing dietary supplements. Nutritional Outlook takes a deep-dive into the newest innovations in joint support ingredients in their recent article. Nitta’s Wellnex Replenwell branded collagen peptide ingredients are named as one of the standout solutions to joint discomfort, along with up-and-comers from the turmeric, eggshell membrane, MSM, and botanical ingredient categories.
According to the article, “collagen supplements recently made the leap from the beauty aisle to the joint health aisle based on studies showing it may relieve joint pain. Research on the interactions between the various types of collagen is now opening up new opportunities for synergistic, combination joint health supplements blending complementary ingredients in a single product.
Other new research on collagen is demonstrating the viability of a personalized nutrition approach. Liz Clarke, CFS, technical marketing manager for Nitta Gelatin (Morrisville, NC), says new research on joint health ingredients goes beyond providing scientific substantiation of health benefits for the general population. Instead, studies are now zeroing in on clinical personalization for specific demographics like younger athletes or seniors with mobility issues.
A recent randomized, double-blind, placebo-controlled clinical trial on Wellnex Replenwell collagen peptides examined the effects of collagen supplementation on joint pain in healthy male university students aged 18 to 21 who were members of the Josai University running club in Sakado, Japan. The students were randomly assigned to receive either 5 g of Replenwell per day (n = 25) or a maltodextrin placebo (n = 21), for eight weeks. After four weeks, the placebo group saw an increase in levels of interleukin-6 (IL-6), a biomarker of inflammation. The collagen peptide group did not see any significant changes in IL-6 levels. The study found that a daily dose of Replenwell taken for four weeks reduced joint discomfort.
“Personalization is the key here,” Clarke says. “We’re seeing significant results with lower dosage rates for active, younger participants than we have in previous studies looking at the effects on older populations with preexisting joint conditions. While it’s common-sense that different populations would have differing needs, being able to quantify that into dosage requirements is new for collagen.”