Our skin changes over time, leading to visible signs of aging, like a loss of elasticity, increased skin roughness, uneven skin tone, wrinkles and fine lines.
Our skin is comprised of two layers, known as the epidermis and dermis. The dermis contains collagen and glycosaminoglycans. Collagen provides integrity and firmness to the skin and is responsible for its strength and elasticity. The degradation of collagen in the skin leads to the reduced skin firmness, enhanced photodamage, and to fine lines and wrinkles.
As we get older, our body’s natural ability to produce collagen decreases. Healthy radiance begins to vanish, and our skin starts to develop ridges, fine lines, uneven tone and age spots, and looses elasticity and moisture.
These signs of aging can be slowed down by maintaining collagen levels in the skin. Since glycine, proline and hydroxyproline are the major amino acids in collagen, replenishing these amino acids may be the key for maintaining collagen levels.
Natural collagen exists in the triple helical rigid structure, which is insoluble and is not absorbed in the human body in its original stage. However, Wellnex Collagen Peptides, the hydrolyzed form of collagen rich in glycine, proline and hydroxyproline, are a natural, bioavailable ingredient that provides these amino acids essential for maintaining healthy collagen in the human body.
Studies have established that collagen peptides are highly digestive and are quickly absorbed when consumed as part of a finished food or supplement. Pharmacological bioavailability trials revealed that two types of collagen dipeptides, prolyl-hydroxyproline (Pro-Hyp) and hydroxyprolyl-glycine (Hyp-Gly), were available at high concentrations for several hours in the human blood stream after oral administration.1)F. Sugihara, et al., J Biosci Bioengi,113,2,202-203, 2012 Read more on bioavailability.
Pro-Hyp and Hyp-Gly also play crucial roles in maintaining skin health conditions and are key components of Wellnex Collagen Peptides.
In an in vitro study of dermal fibroblast, Pro-Hyp and Hyp-Gly enhanced the proliferation and Pro-Hyp stimulate the production of Hyaluronic acid.2)H. Ohara, et al., J Dermatol, 37, 330-338, 2010 These invents suggest the linkage to the improvements of clinical skin conditions, namely increasing skin moisture and elasticity and reducing skin roughness and UV spots.3)F. Sugihara, et al., Health Sciences, 28, 2, 2012. Studies show, as demonstrated in the below graphs, that Wellnex Collagen Peptides:
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|1.||↑||F. Sugihara, et al., J Biosci Bioengi,113,2,202-203, 2012|
|2.||↑||H. Ohara, et al., J Dermatol, 37, 330-338, 2010|
|3.||↑||F. Sugihara, et al., Health Sciences, 28, 2, 2012|