As our skin changes over time, we may notice visible signs of aging such as loss of elasticity, increased skin roughness, uneven skin tone, and fine lines or wrinkles.
Our skin is comprised of two layers, known as the epidermis and dermis. The dermis contains collagen and glycosaminoglycans. Collagen provides integrity and firmness to the skin, and is responsible for its strength and elasticity. The degradation of collagen in the skin leads to the reduced skin firmness, enhanced photo-damage, fine lines and wrinkles.
As we get older, our body’s natural ability to produce collagen decreases. Healthy radiance begins to vanish, and our skin starts to develop ridges, fine lines, uneven tone and age spots, and looses elasticity and moisture.
These signs of aging can be slowed down by maintaining collagen levels in the skin. Because glycine, proline and hydroxyproline are the major amino acids in collagen, replenishing these amino acids may be the key for maintaining collagen levels.
Natural collagen exists in the triple helical rigid structure, which is insoluble and is not absorbed in the human body in its native form. However, Wellnex collagen peptides, the hydrolyzed form of collagen rich in glycine, proline and hydroxyproline, are a natural, bioavailable ingredient that provides these amino acids essential for maintaining healthy collagen in the human body.
Studies have established that collagen peptides are highly digestible, and are quickly absorbed when consumed as part of a finished food or supplement. Pharmacological bioavailability trials revealed that two types of collagen dipeptides, prolyl-hydroxyproline (Pro-Hyp) and hydroxyprolyl-glycine (Hyp-Gly), were available at high concentrations for several hours in the human blood stream after oral administration (F. Sugihara, et al., J Biosci Bioengi,113,2,202-203, 2012) Read more on bioavailability.
Key dipeptides Pro-Hyp and Hyp-Gly also play crucial roles in supporting healthy skin, and are just some of the bioactive components of Wellnex collagen peptides.
In an in vitro study of dermal fibroblast (specialized skin cells), dipeptides Pro-Hyp and Hyp-Gly enhanced cellular proliferation, and Pro-Hyp also stimulated the production of Hyaluronic acid (H. Ohara, et al., J Dermatol, 37, 330-338, 2010). These findings suggest a correlation between the presence of key dipeptides Pro-Hyp and Hyp-Gly and skin improvements noted in a later study ; including increased skin moisture and elasticity and reduced roughness and UV spots (F. Sugihara, et al., Health Sciences, 28, 2, 2012). In a 2015 randomized, double-blind, placebo-controlled clinical study, a 2.5g/day serving of Wellnex collagen peptides have been found to increase skin hydration and elasticity, while reducing roughness, in as little as 4 weeks (F. Sugihara, et al., Jpn Pharmacol Ther, 43, 67-70, 2015).
Clinical studies indicate that ingestion of Wellnex collagen peptides is linked to*:
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.